Jürgen Klopp has not beaten Southampton in four league meetings but, after three straight wins in all competitions and with his squad nearing full fitness, he said: “Now is a good moment to strike back.” Adam Lallana, who is yet to make an appearance this season, is unlikely to feature against his old club but Sadio Mané could play after a hamstring scare. Mauricio Pellegrino, who played 13 times for Liverpool in 2005, has maintained Southampton’s defensive discipline, since replacing Claude Puel, but scoring has been a struggle. His team have conceded and scored only three goals away from home this term. Andy Hunter
Kick-off Saturday 3pm
Venue Anfield
Last season Liverpool 0 Southampton 0
Referee Mike Jones
This season G4, Y16, R0, 4.00 cards per game
Odds H 4-9 A 8-1 D 17-4
Liverpool
Subs from Karius, Alexander-Arnold, Lallana, Milner, Wijnaldum, Klavan, Robertson, Flanagan, Grujic, Woodburn, Solanke, Markovic, Oxlade-Chamberlain, Ings
Doubtful Mané (hamstring)
Injured Ward (back, 25 Nov), Clyne (back, Feb)
Suspended None
Form WDDLWW
Discipline Y14 R1
Leading scorer Salah 7
Southampton
Subs from McCarthy, Taylor, Stephens, Hoedt, Tadic, Long, Austin, McQueen, Bednarek, Hojbjerg, Gardos, Targett, Sims, Hesketh
Doubtful Hoedt (knee)
Injured Lemina (ankle, 26 Nov), Pied (groin, unknown)
Suspended None
Form LLDWDL
Discipline Y10 R0
Leading scorer Gabbiadini 3