José Mourinho is well equipped to exploit Liverpool’s weaknesses with the power, organisation and counter-attacking style of his joint league leaders but that would require a different strategy to what he successfully employed at Anfield last season. Marouane Fellaini and Paul Pogba are big misses for Manchester United but Sadio Mané’s absence will be felt by Jürgen Klopp, too. Liverpool’s performances have not been as bad as recent results indicate but they can ill-afford to fall 10 points behind their arch rivals so early in the season. Both sides have opportunity to deliver a statement of intent. Andy Hunter
Kick-off Saturday 12.30pm
Venue Anfield
Last season Liverpool 0 Man Utd 0
Live Sky Premier League
Referee Martin Atkinson
This season G4, Y11, R1, 3 cards per game
Odds H 9-5 A 9-5 D 5-2
Liverpool
Subs from Karius, Ward, Sturridge, Klavan, Gomez, Milner, Robertson, Flanagan, Grujic, Woodburn, Solanke, Oxlade-Chamberlain, Markovic, Ings
Doubtful None
Injured Lallana (thigh, Nov), Mané (hamstring, Nov), Clyne (back, unknown)
Suspended None
Form WWLDWD
Discipline Y13 R1
Leading scorer Salah 4
Manchester Utd
Subs from Pereira, Romero, Tuanzebe, Lindelof, Mata, Lingard, McTominay, Mitchell, Darmian, Blind, Shaw, Smalling
Doubtful None
Injured Carrick (calf, 28 Oct), Fellaini (knee, Nov), Ibrahimovic, Rojo (both knee, Dec), Pogba (hamstring, unknown)
Suspended None
Form WWDWWW
Discipline Y9 R0
Leading scorer Lukaku 7