Southampton vs Brighton: Team news, kick-off time, likely line-ups, odds and stats from the Premier League clash

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Ahead of the Premier League's weekend action, Sportsmail will be providing you with team news, betting odds and Opta stats. Here is all you need to know as Southampton take on Brighton at St Mary's on Wednesday night.

Brighton and Southampton played out a 1-1 draw at the Amex Stadium back in October

Southampton vs Brighton (St Mary's)

Team news

Southampton 

Guido Carrillo could make his Premier League debut for Southampton when they host Brighton on Wednesday night.

The striker, signed from Monaco last week, came on as a late substitute in the FA Cup win over Watford but is now pushing for a start despite not being completely match-fit.

Ryan Bertrand (hamstring) was withdrawn during the victory over the Hornets but could feature, while Charlie Austin is back in training although not ready for a return following his own hamstring issue.

Provisional squad: Forster, McCarthy, Taylor, Cedric, Pied, Stephens, Hoedt, Bertrand, McQueen, Gardos, Lemina, Romeu, Hojbjerg, Davis, Ward-Prowse, Rose, Tadic, Redmond, Long, Carrillo, Gabbiadini.

Guido Carrillo could make his Premier League debut for Southampton when they host Brighton

Brighton 

Leonardo Ulloa is in contention to make his second Brighton debut at Southampton after rejoining on loan from Leicester.

Fellow new signing Jurgen Locadia is still recovering from a hamstring injury but should begin training next week.

The Seagulls are waiting to discover the extent of the ankle injury suffered by winger Jiri Skalak against Middlesbrough at the weekend.

Provisional squad: Ryan, Krul, Bong, Bruno, Duffy, Dunk, Hunemeier, Rosenior, Goldson, Schelotto, Suttner, Kayal, Propper, Knockaert, Stephens, March, Izquierdo, Gross, Ulloa, Murray, Hemed, Baldock.

Leonardo Ulloa is in line to make his second Brighton debut after joining the Seagulls on loan

Key match stats (supplied by Opta)

After winning two of their first three top-flight clashes against Brighton, Southampton have won just one of the last six (D3 L2). 

Brighton have failed to score in their last two away league trips to Southampton, they last went three in a row without scoring there in November 1953.

Southampton have only lost one of their last 27 Premier League home games against newly promoted teams (W17 D9) and are unbeaten in each of the last 11.

Brighton are yet to score in their three previous Premier League midweek games (Tuesday and Wednesday), drawing 0-0 with Crystal Palace and losing 2-0 against both Tottenham and Chelsea. 

Saints are winless in their last 11 Premier League games (D6 L5), just one short of their longest ever winless run in the competition (12 games ending March 1995). 

The Seagulls have scored fewer away goals than any other Premier League side this season (5), failing to score in nine of their 12 games on the road this season, including each of the last six. 

Pascal Gross has had a hand in 53% of Brighton’s 17 Premier League goals so far this campaign

Southampton have scored in each of their last six Premier League home games, netting nine goals in total. Their previous nine at St Mary’s in the competition had come over a period of 14 games. 

Indeed, Saints have also conceded in each of those six games – only once in the Premier League have they had a longer run of both scoring and conceding in home games (8 games between February and August 2016). 

Saints have dropped a league-high nine points from leading positions in Premier League home games this season. 

Pascal Gross has had a hand in 53% of Brighton’s 17 Premier League goals this season (4 goals, 5 assists), the highest ratio in the division.